• ABC super family proteins are

  2025-02-11

  

  ABC super family proteins are found in all forms of life and ABC-F subfamily of proteins are involved in cellular processes such as translational control and antibiotic resistance by ribosomal protection [3], [5]. The Mtb ABC proteins that do not contain transmembrane domains have not been studied [

• Inactivation of the proton pump comes

  2025-02-11

  

  Inactivation of the proton pump comes with luminal alkalinization of the targeted vesicles such as lysosomes (Fig. 2b). Lysosome pH can also be raised stoichiometrically by addition of a membrane-permeable weak sgk inhibitor such as methylamine or chloroquine which accumulates in its protonated, non

• br Experimental Section br Results and Discussion br Conclus

  2025-02-11

  

  Experimental Section Results and Discussion Conclusions The advantages of the novel enzymo-chemical method for Mn and Co assay are simplicity of analytical procedure and economic effect due to the usage of only one enzyme in the form of apo-enzyme. An effectiveness of the apo-arginase-based

• However one should keep in mind that these results may

  2025-02-11

  

  However, one should keep in mind that these results may not reflect exactly in vivo antioxidant activity. Many other issues such as absorption, metabolism and physicochemical properties of different antioxidants must also be considered (Prior et al., 2007, Wu et al., 2004). Some research groups are

• br Materials and methods br

  2025-02-11

  

  Materials and methods Results Discussion Endophilin A1 is a membrane-binding protein that is mainly distributed in the central nervous system (Giachino et al., 1997), localizes in the dendritic shafts and spines of mature neurons (Yang et al., 2015), and relates to the function and morpholo

• br cDNA cloning gene structure and

  2025-02-11

  

  cDNA cloning, gene structure and chromosomal localization The cDNA for the leukocyte-type 12S-lipoxygenase was first cloned from porcine leukocytes [9], and later from mouse [10], [11], rat [12], [13], bovine [14] and rabbit [15] sources. The cDNA for the platelet-type 12S-lipoxygenase cDNA has b

• With regard to participation of

  2025-02-11

  

  With regard to participation of the 12S-lipoxygenase in diabetes mellitus, inconsistent results have been obtained. Earlier studies demonstrated that the leukocyte-type 12S-lipoxygenase is specifically expressed in pancreatic b-cells and is involved in regulating glucose-stimulated insulin secretion

• br Depletion of serum amino acids Currently the only antican

  2025-02-11

  

  Depletion of serum amino acids Currently, the only anticancer agents that directly target amino DOI hydrochloride metabolism are bacterial l-asparaginases (from Escherichia coli and Erwinia chrysanthemi), which are FDA-approved for treatment of pediatric and adult ALL. A potential complication o

• Since the first studies of betaine aldehyde oxidation

  2025-02-11

  

  Since the first studies of betaine aldehyde oxidation in rats [13], the participation of betaine in the detoxification of homocysteine has well described, considering the activity of other RG2833 as betaine homocysteine methyltransferase and methionine synthase. But, there is a lack of attention wh

• It is important to note that stable amnesia

  2025-02-10

  

  It is important to note that stable amnesia is, apparently, a general biological phenomenon and can be found in different animal species. In studies on rats, it was found that if reconsolidation of conditioned olfactory aversion memory was impaired by the antagonist of NMDA glutamate receptors, amne

• Ferrostatin-1 br Actin cytoskeleton in protrusion Pushing fo

  2025-02-10

  

  Actin cytoskeleton in protrusion Pushing force driving membrane protrusion is generated by polymerizing Ferrostatin-1 filaments organized either into branched networks or parallel bundles. Branched networks are assembled through Arp2/3 complex-dependent actin nucleation and drive protrusion of l

• Renal cell carcinoma RCC accounts

  2025-02-10

  

  Renal cell carcinoma (RCC) accounts for more than 12,000 cancer deaths in the United States (Jemal et al., 2003). The current treatment includes surgical resection followed by interleukin-2 or Interferon-α treatment. Some patients experience distant metastatic lesions of RCC. In the last 5 years, re

• With the treatment options available today

  2025-02-10

  

  With the treatment options available today including a combination of symptomatic treatments and general immunosuppression, many MG patients can lead productive lives [1], [4], [20]. The frequency of death has decreased due to improved management and detection of milder cases. At present, the overal

• br Results br Discussion Dopamine regulates

  2025-02-10

  

  Results Discussion Dopamine regulates behavioral responses to nicotine in Drosophila (Bainton et al., 2000), but neurochemical measurements of dopamine after nicotine stimulation had not been made. Here, we demonstrate for the first time that the stimulation of nAChRs causes dopamine release i

• Finasteride was the first steroidal reductase inhibitor appr

  2025-02-10

  

  Finasteride (13) was the first steroidal 5α-reductase inhibitor approved by the US Food and Drug Administration (FDA) in 1992 for treatment of BPH. In fact, long term clinical studies with this drug demonstrated a sustained reduction of the prostatic specific antigen and an overall improvement in BH

13446 records 12/897 page Previous Next First page 上5页 1112131415 下5页 Last page